NewsPronto

 
Men's Weekly

.

USA Conversation

The Conversation USA

The Conversation USA

90% of drugs fail clinical trials – here's one way researchers can select better drug candidates

  • Written by Duxin Sun, Professor of Pharmaceutical Sciences, University of Michigan
imageThe majority of drug failures are attributed to lack of clinical efficacy and high toxicity.Andrew Brookes/Image Source via Getty Images

It takes 10 to 15 years and around US$1 billion to develop one successful drug. Despite these significant investments in time and money, 90% of drug candidates in clinical trials fail. Whether because they...

Read more: 90% of drugs fail clinical trials – here's one way researchers can select better drug candidates

More Articles ...

  1. Ancient DNA helps reveal social changes in Africa 50,000 years ago that shaped the human story
  2. Why Muslim women choose to wear headscarves while participating in sports
  3. US counties with more civic engagement tend to have more women on local company boards of directors
  4. Putin's antagonism toward Ukraine was never just about NATO – it's about creating a new Russian empire
  5. COVID-19 pandemic poses unique challenges for students who are homeless
  6. COVID-19 cases on campus could surge after spring break unless students take certain precautions
  7. How AI is shaping the cybersecurity arms race
  8. Putin’s public approval is soaring during the Russia-Ukraine crisis, but it's unlikely to last
  9. Taxpayers should expect serious delays from the IRS this year – a tax scholar offers tips but says only Congress can fix the underlying problem
  10. Why the cost of mitigating climate change can't be boiled down to one right number, despite some economists' best attempts
  11. First solar canal project is a win for water, energy, air and climate in California
  12. How teachers enter the profession affects how long they stay on the job
  13. More migrants are dying along the US-Mexico border, but it's hard to say how big the problem actually is
  14. Burying the past and building the future in post-apartheid South Africa
  15. Think therapy is navel-gazing? Think again
  16. What is 3G and why is it being shut down? An electrical engineer explains
  17. Farmers are overusing insecticide-coated seeds, with mounting harmful effects on nature
  18. Ukraine crisis: Putin recognizes breakaway regions, Biden orders limited sanctions – 5 essential reads
  19. How scammers like Anna Delvey and the Tinder Swindler exploit a core feature of human nature
  20. A mild-mannered biker triggered a huge debate over humans' role in climate change – in the early 20th century
  21. Why do humans have bones instead of cartilage like sharks?
  22. Why Ukrainian Americans are committed to preserving Ukrainian culture – and national sovereignty
  23. What will the Winter Olympics look like in a warming world? Snowmaking can defy climate change for only so long
  24. How climate change threatens the Winter Olympics' future – even snowmaking has limits for saving the Games
  25. How climate change threatens the Winter Olympics' future
  26. How climate change threatens the Winter Olympics' future – even snowmaking has limits for saving it
  27. Dunkology 101: How the NBA could take a more scientific approach to scoring the slam dunk
  28. 1 in 4 Americans are covered by Medicaid or CHIP – a program that insures low-income kids
  29. What's insider trading and why it’s a big problem
  30. The US doesn't need to wait for an invasion to impose sanctions on Russia – it could invoke the Magnitsky Act now
  31. Calling the coronavirus the 'Chinese virus' matters – research connects the label with racist bias
  32. Tens of thousands of Afghan evacuees made it to the US – here's how the resettlement process works
  33. What's the IOC – and why doesn't it do more about human rights issues related to the Olympics?
  34. The Cold War, modern Ukraine and the spread of democracy in the former Soviet bloc countries
  35. What are false flag attacks – and could Russia make one work in the information age?
  36. Rising costs of climate change threaten to make skiing a less diverse, even more exclusive sport
  37. Happy Twosday! Why numbers like 2/22/22 have been too fascinating for over 2,000 years
  38. The Supreme Court could hamstring federal agencies' regulatory power in a high-profile air pollution case
  39. Want better child care? Invest in entrepreneurial training for child care workers
  40. Female business travelers pay less than their male colleagues because they tend to book earlier
  41. Can religion and faith combat eco-despair?
  42. Yoko Ono's prophetic vision of self-care
  43. Anti-Asian violence spiked in the US during the pandemic, especially in blue-state cities
  44. Deer, mink and hyenas have caught COVID-19 – animal virologists explain how to find the coronavirus in animals and why humans need to worry
  45. Invading Ukraine may never have been Putin's aim – the threat alone could advance Russia's goals
  46. All American presidents have lied – the question is why and when
  47. The Ancient Greeks also lived through a plague, and they too blamed their leaders for their suffering
  48. Super Bowl ads turn up the volume on cryptocurrency buzz: 6 essential reads about digital money and the promise of blockchain
  49. For bullied teens, online school offered a safe haven
  50. Despite its disastrous effects, COVID-19 offers some gifts to medicine – an immunology expert explains what it can teach us about autoimmune disease