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How does Narcan work? Mapping how it reverses opioid overdose can provide a molecular blueprint for more effective drugs

  • Written by Saif Khan, Ph.D. Candidate in Biology, University of Southern California
imageNaloxone competes with opioids for the same receptor on the surface of neurons.Matt Rourke/AP Photo

Naloxone, also known by the brand name Narcan, is one of the most important drugs in the United States’ fight against the opioid crisis. It reverses an opioid overdose nearly instantly, restarting breathing in a person who was unresponsive...

Read more: How does Narcan work? Mapping how it reverses opioid overdose can provide a molecular blueprint...

Absence of evidence is not evidence of absence – and that affects what scientific journals choose to publish

  • Written by Mark Louie Ramos, Assistant Research Professor of Health Policy and Administration, Penn State
imageCareful planning and analysis are part of trying to reduce the chance of a false-positive finding.Arnon Mungyodklang/iStock via Getty Images Plus

Should you believe the findings of scientific studies? Amid current concerns about the public’s trust in science, old arguments are resurfacing that can sow confusion.

As a statistician involved in...

Read more: Absence of evidence is not evidence of absence – and that affects what scientific journals choose...

George Plimpton’s 1966 nonfiction classic ‘Paper Lion’ revealed the bruising truths of Detroit Lions training camp

  • Written by Stephen Siff, Associate Professor of Journalism, Miami University
imageGreen Bay Packers wide receiver Romeo Doubs (87) and Detroit Lions cornerback Terrion Arnold (6) show off their athleticism on Sept. 7, 2025.AP Photo/Matt Ludtke

As the Detroit Lions barrel toward a Thanksgiving Day game with the Green Bay Packers, some die-hard fans may be fantasizing about what it would be like to be on the field themselves:...

Read more: George Plimpton’s 1966 nonfiction classic ‘Paper Lion’ revealed the bruising truths of Detroit...

Pentagon investigation of Sen. Mark Kelly revives Cold War persecution of Americans with supposedly disloyal views

  • Written by Gregory A. Daddis, Professor and Melbern G. Glasscock Endowed Chair in American History, Texas A&M University
imageArizona Sen. Mark Kelly speaks at a town hall meeting hosted by the South Carolina Democratic Party in Columbia, S.C., on Sept. 12, 2025. Bill Clark/CQ-Roll Call, Inc via Getty Images

In an unprecedented step, the Department of Defense announced online on Nov. 24, 2025, that it was reviewing statements by U.S. Sen. Mark Kelly, a Democrat, who is a...

Read more: Pentagon investigation of Sen. Mark Kelly revives Cold War persecution of Americans with...

A database could help revive the Arapaho language before its last speakers are gone

  • Written by Andrew Cowell, Professor of Linguistics, University of Colorado Boulder
imageThere are fewer than 100 speakers of the Arapaho language today.Mark Makela/GettyImages

I was hired at the University of Colorado Boulder in 1995 as a language professor. I relocated from Hawaii, where I had learned the Hawaiian language.

When I arrived in Colorado, I decided I needed to learn about the Indigenous language of the Boulder and Denver...

Read more: A database could help revive the Arapaho language before its last speakers are gone

How food assistance programs can feed families and nourish their dignity

  • Written by Joslyn Brenton, Assistant Professor of Sociology, Ithaca College
imageFood assistance does more good when it doesn't make people feel bad for needing help.SolStock/E+ via Getty Images

The 2025 government shutdown drew widespread attention to how many Americans struggle to get enough food. For 43 days, the more than 42 million Americans who receive Supplemental Nutrition Assistance Program benefits had to find other...

Read more: How food assistance programs can feed families and nourish their dignity

What makes a true Santa is inside – and comes with the red suit

  • Written by Christina Hymer, Assistant Professor of Management and Entrepreneurship, University of Tennessee
imageMembers of the Fraternal Order of Real Bearded Santas meet at Pink's restaurant at Knott's Berry Farm before the holiday rush in 2009.Business Wire via AP

When you picture Santa Claus, a white, bearded, overweight and jolly man who dashes around delivering gifts to children during the Christmas season probably comes to mind. Yet, not everyone who...

Read more: What makes a true Santa is inside – and comes with the red suit

‘Without prejudice’: What this 2-word legalese means for the dismissed charges against James Comey and Letitia James

  • Written by Ray Brescia, Associate Dean for Research and Intellectual Life, Albany Law School
imageFormer FBI Director James Comey is sworn in remotely at a hearing of the Senate Judiciary Committee in Washington on Sept. 30, 2020.Ken Cedeno-Pool/Getty Images

A federal judge on Nov. 24, 2025, dismissed the indictments against former FBI Director James B. Comey and New York Attorney General Letitia James, blocking the Department of...

Read more: ‘Without prejudice’: What this 2-word legalese means for the dismissed charges against James Comey...

From concrete to community: How synthetic data can make urban digital twins more humane

  • Written by Wei Zhai, Associate Professor of Public Affairs and Planning, University of Texas at Arlington
imageHow people behave is a critical element of how cities function.Ahmed Deeb/picture alliance via Getty Images

When city leaders talk about making a town “smart,” they’re usually talking about urban digital twins. These are essentially high-tech, 3D computer models of cities. They are filled with data about buildings, roads and...

Read more: From concrete to community: How synthetic data can make urban digital twins more humane

The ChatGPT effect: In 3 years the AI chatbot has changed the way people look things up

  • Written by Deborah Lee, Professor and Director of Research Impact and AI Strategy, Mississippi State University
imageChatGPT has become the go-to app for hundreds of millions of people.AP Photo/Kiichiro Sato

Three years ago, if someone needed to fix a leaky faucet or understand inflation, they usually did one of three things: typed the question into Google, searched YouTube for a how-to video or shouted desperately at Alexa for help.

Today, millions of people...

Read more: The ChatGPT effect: In 3 years the AI chatbot has changed the way people look things up

More Articles ...

  1. When darkness shines: How dark stars could illuminate the early universe
  2. Fern stems reveal secrets of evolution – how constraints in development can lead to new forms
  3. A quarter of early child care educators in Colorado reported mistreatment from co-workers
  4. Sea level doesn’t rise at the same rate everywhere – we mapped where Antarctica’s ice melt would have the biggest impact
  5. Automated systems decide which homeless Philadelphians get housing and who stays on the street – often in ways that feel arbitrary to those waiting
  6. Treating love for work like a virtue can backfire on employees and teams
  7. Colleges teach the most valuable career skills when they don’t stick narrowly to preprofessional education
  8. Thousands of genomes reveal the wild wolf genes in most dogs’ DNA
  9. Peace plan presented by the US to Ukraine reflects inexperienced, unrealistic handling of a delicate situation
  10. Writing builds resilience by changing your brain, helping you face everyday challenges
  11. More than half of new articles on the internet are being written by AI – is human writing headed for extinction?
  12. Nonprofit news outlets are often scared that selling ads could jeopardize their tax-exempt status, but IRS records show that’s been rare
  13. How will the universe end?
  14. AI is making spacecraft propulsion more efficient – and could even lead to nuclear-powered rockets
  15. Mid-Atlantic mushroom foragers collect 160 species for food, medicine, art and science
  16. We created health guidelines for fighting loneliness - here’s what we recommend
  17. Nick Fuentes is a master of exploiting the current social media opportunities for extremism
  18. What Robert F. Kennedy Jr. didn’t tell you about ‘Operation Northwoods,’ the false flag operation he loves to denounce
  19. From invasive species tracking to water security – what’s lost with federal funding cuts at US Climate Adaptation Science Centers
  20. Just follow orders or obey the law? What US troops told us about refusing illegal commands
  21. Colorado is pumping the brakes on first-of-its-kind AI regulation to find a practical path forward
  22. The plague of frog costumes demonstrates the subversive power of play in protests
  23. John Fetterman is an unusual politician – but his rise from borough mayor to US senator reflects a recent trend
  24. Making GLP-1 weight loss drugs cheaper isn’t enough to address America’s obesity problem – here’s why
  25. Off-label use of COVID-19 vaccines was once discouraged but has become common amid new guidelines
  26. From ‘mail-order brides’ to ‘passport bros,’ the international dating industry often sells traditional gender roles
  27. $2B Counter-Strike 2 crash exposes a legal black hole: Your digital investments aren’t really yours
  28. Farmers – long Trump backers – bear the costs of new tariffs, restricted immigration and slashed renewable energy subsidies
  29. First Amendment in flux: When free speech protections came up against the Red Scare
  30. AI is providing emotional support for employees – but is it a valuable tool or privacy threat?
  31. Who wins and who loses as the US retires the penny
  32. ‘Jeffrey Epstein is not unique’: What his case reveals about the realities of child sex trafficking
  33. College students are now slightly less likely to experience severe depression, research shows – but the mental health crisis is far from over
  34. 50 years after Franco’s death, giving a voice to Spanish dictator’s imprisoned mothers
  35. Beyond the habitable zone: Exoplanet atmospheres are the next clue to finding life on planets orbiting distant stars
  36. How climate finance to help poor countries became a global shell game – donors have counted fossil fuel projects, airports and even ice cream shops
  37. The Dayton Peace Accords at 30: An ugly peace that has prevented a return to war over Bosnia
  38. Orthodox Judaism is making space for women’s religious leadership – even without traditional ordination
  39. Learning with AI falls short compared to old-fashioned web search
  40. Florida residents’ anxiety is linked to social media use and varies with age, new study shows
  41. Vice President Dick Cheney’s life followed the arc of the biggest breakthroughs in cardiovascular medicine
  42. Why MAGA is obsessed with Epstein − and why the files are unlikely to dent loyalty to Trump
  43. Why MAGA is so concerned with Epstein − and why the files are unlikely to dent loyalty to Trump
  44. How pecans went from ignored trees to a holiday staple – the 8,000-year history of America’s only native major nut
  45. How pecans went from ignored trees to a holiday staple – the 8,000-year history of America’s only native major nut crop
  46. When fake data is a good thing – how synthetic data trains AI to solve real problems
  47. Research breakthroughs often come through collaborations − attacks on academic freedom threaten this vital work
  48. Black families pay more to keep their houses warm than average American families
  49. Black student unions are under pressure – here’s what they do and how they help Black students find community
  50. Americans are unprepared for the expensive and complex process of aging – a geriatrician explains how they can start planning